Company History:

Owing to the fact that the currently available methods of treatments for osteoarthritic diseases are invasive, and recovery is often complicated by age, inflammation and patients prolonged reliance on a variety of pain medications, the founders of TissueGene sought to find alternative and novel therapuetics for orthopedic disease. The overall deteriorating quality of life associated with complications resulting are from prolonged and difficult recoveries to a variety of degenerative disease and inflammatory responses. In light of this, TissueGene has focused its attention on the regenerative aspects of ones own body to solve these problems.

Starting in 1997, the founders of TissueGene sought to uncover different surgical and gene-based therapeutics for a variety of arthritic conditions. The diligence soon paid off in the form of the first successful animal model for cartilage repair. Subsequently, in the middle of 1999, TissueGene, Inc was incorporated in the United States.

TissueGene's initial findings resulted in the focused development of a proprietary cell mediated genetic technology capable of treating and regenerating damaged tendons, ligaments, cartilage and bones. The company began using a form of cell mediated gene therapy to deliver a regenerative protein to damaged tissue, which catalyzes rapid and permanent repair of the injured site without the need for surgery.

By the end of 1999, TissueGene had successfully recruited several scientists and began assembling a top notch management team. With the laboratory operational, the company focused on expanding its patent portfolio and enhancing its business model by applying for international patent protection.

In the meantime, TissueGene relocated its laboratory and business operations to the technology corridor in Gaithersburg, Maryland. Soon after moving to the east coast, the company was granted its first US patent.

TissueGene has continued to enhance its global partnerships in order to effectively utilize resources in the most efficient manner. Our innovative cost control mechanisms, vision for strategic alliances, international partnerships and outsourcing is paving the way for the future success of the company in this competitive and global marketplace.